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Year : 2005  |  Volume : 6  |  Issue : 3  |  Page : 98-103

Myocardial performance index evaluated with tissue doppler echocardiography at early, intermediate and late phase of acute myocardial infarction

1 Laboratory of Ecochardiography, Second University of Naples- San Gennaro. Hospital-Naples, Italy
2 Cardiovascular Research Center-Second University of Naples- Naples, Italy
3 XII Medical Division. A.O.R.N. . A. Cardarelli. Naples, Italy
4 Cardiology Division-.San Gennaro. Hospital-Naples, Italy

Correspondence Address:
Federico Cacciapuoti
Cattedra di Medicina Interna, Facoltą di Medicina e Chirurgia, Seconda Universitą di Napoli, Piazza L. Miraglia, 2 80138-Naples
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Source of Support: None, Conflict of Interest: None

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In this study, ejection fraction% (EF%) and myocardial performance index (MPI) were recorded in 67 survivors at early, intermediate and late phase of acute myocardial infarction (AMI) .EF% was echocardiographically obtained by the Simpson's method; MPI was calculated using Tissue Doppler Echocardiography (TDE) derived from isovolumetric contraction time (ICT); isovolumetric relaxation time (IRT) and ejection time (ET). Results were compared with those obtained in 70 controls matched for age and sex. At hospital discharge (early evaluation), EF% was < 50% with significant increase in MPI in respect to the healthy controls (increase in ICT, significant reduction in ET and IRT was unchanged). Six months later (intermediate evaluation), EF% still resulted in < 50%, MPI was slightly reduced with further increase in ICT and IRT in comparison to the early evaluation, and slight reduction in ET. Finally, one year later (late evaluation), in spite of increase in EF>50%, MPI was still increased, with slight rise in ICT, almost normalization in ET, but more evident increase in IRT. The outcomes of MPI demonstrate that in post-AMI patients, late prevalent diastolic ventricular dysfunction occurs following an early systolic dysfunction. In this study, EF% appears to be less sensitive than MPI in defining late post-AMI left ventricular dysfunction. Finally, TDE seems to be more sensitive than conventional Doppler method in measuring MPI.

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