CASE REPORT |
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Year : 2013 | Volume
: 14
| Issue : 4 | Page : 179-181 |
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Fatal acute right heart failure in gastric cancer patients
Sang-Hoon Seol, Bo-Min Park, Han-Young Jin, Doo-Il Kim
Department of Internal Medicine, Division of Cardiology, Inje University College of Medicine, Haeundae Paik Hospital, Busan, Korea
Correspondence Address:
Doo-Il Kim Department of Medicine, Inje University College of Medicine, Haeundae Paik Hospital, 1435 Jwa-dong, Haeundae-gu, Busan Korea
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/1995-705X.126883
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Pulmonary tumor thrombotic microangiopathy (PTTM) is a rare condition causing pulmonary artery hypertension and acute right heart failure in patients with cancer. However, chest computer tomography shows negative finding of pulmonary thromboembolism. Serum D-dimer level may be elevated. Echocardiography reveals a dilated right ventricle and feature of pulmonary artery hypertension. Establishing this diagnosis can be very difficult, and most cases are diagnosed during autopsy, although a history of cancer may be a predictor. PTTM should be considered in all patients with apparent pulmonary artery hypertension and elevated D-dimer level, particularly when the patient is known to have an underlying malignancy, especially adenocarcinoma and most of all, the clinical manifestation is very rapidly progressive. |
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