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   2008| Mar-May  | Volume 9 | Issue 1  
    Online since June 17, 2010

 
 
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CASE REPORT
Meandering vessels: A sign of arterial tortuosity on plain chest radiography
Venkatraman Bhat, Ahmed Al Muzrakchi
Mar-May 2008, 9(1):24-26
  14,907 126 -
HISTORY OF MEDICINE
The Magnificent Century of Cardiothoracic Surgery
Amer Chaikhouni
Mar-May 2008, 9(1):48-51
  3,941 118 -
REVIEW ARTICLE
Aneurysm of the sinuses of valsalva: Report of two cases and review of the literature
Saad Alkhafaji, Cornelia S Carr, Abdul-Aziz M Alkhulaifi, Abdulwahed Almulla, Akhlaque Bhat, Amer Chaikhouni
Mar-May 2008, 9(1):18-23
  2,597 166 -
ORIGINAL ARTICLE
Reduction of microvascular obstruction and myocardial infarct size with hypothermia
Matthias Gotberg, Goran K Olivecrona, Henrik Engblom, Martin Ugander, Jesper van der Pals, Einar Heiberg, Hakan Arheden, David Erlinge
Mar-May 2008, 9(1):6-17
Background: The aim of this study was to evaluate the combination of a rapid intravenous infusion of cold saline and endovascular hypothermia in a closed chest pig infarct model. Methods: Pigs were randomized to pre-reperfusion hypothermia (n = 7), post-reperfusion hypothermia (n = 7) or normothermia (n = 5). A percutaneous coronary intervention balloon was inflated in the left anterior descending artery for 40 min. Hypothermia was started after 25 min of ischemia or immediately after reperfusion by infusion of 1000 ml of 4΀C saline and endovascular hypothermia. Area at risk was evaluated by in vivo SPECT. Infarct size was evaluated by ex vivo MRI. Results: Pre-reperfusion hypothermia reduced infarct size/area at risk by 43% (46 ± 8%) compared to post-reperfusion hypothermia (80 ± 6%, p < 0.05) and by 39% compared to normothermia (75 ± 5%, p < 0.05). Pre-reperfusion hypothermia infarctions were patchier in appearance with scattered islands of viable myocardium. Pre-reperfusion hypothermia abolished (0%, p < 0.001), and post-reperfusion hypothermia significantly reduced microvascular obstruction (10.3 ± 5%; p < 0.05), compared to normothermia: (30.2 ± 5%). Conclusion: Rapid hypothermia with cold saline and endovascular cooling before reperfusion reduces myocardial infarct size and microvascular obstruction. A novel finding is that hypothermia at the onset of reperfusion reduces microvascular obstruction without reducing myocardial infarct size. Intravenous administration of cold saline combined with endovascular hypothermia provides a method for a rapid induction of hypothermia suggesting a potential clinical application.
  2,248 88 -
ART AND MEDICINE
Healing Eye
Rachel Hajar
Mar-May 2008, 9(1):47-47
  1,609 72 -
GULF RACE REGISTRY
Commentary GHA acute coronary syndrome registry: Historical perspective
HA Hajar Albinali
Mar-May 2008, 9(1):28-46
  1,366 79 -
A PICTURE IS WORTH A THOUSAND WORDS
A nail through the heart
Cornelia Carr
Mar-May 2008, 9(1):27-27
  1,375 69 -
CARDIOVASCULAR NEWS
Cardiovascular News

Mar-May 2008, 9(1):2-5
  1,322 76 -
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