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  Citation statistics : Table of Contents
   2012| January-March  | Volume 13 | Issue 1  
    Online since May 26, 2012

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C-reactive protein as a predictor of adverse outcome in patients with acute coronary syndrome
AS Sheikh, S Yahya, NS Sheikh, AA Sheikh
January-March 2012, 13(1):7-12
DOI:10.4103/1995-705X.96660  PMID:22754634
Background and Objectives: The acute-phase reactant C-reactive protein (CRP) has been shown to reflect systemic and vascular inflammation and to predict future cardiovascular events. The objective of this study was to evaluate the prognostic value of CRP in predicting cardiovascular outcome in patients presenting with acute coronary syndromes. Patients and Methods: This prospective, single-centered study was carried out by the Department of Pathology in collaboration with the Department of Cardiology, Bolan Medical College Complex Quetta, Balochistan, Pakistan from January 2009 to December 2009. We studied 963 consecutive patients presenting with chest pain to Accident and Emergency Department. Patients were divided into four groups. Group-1 comprised patients with unstable angina; group-2 included patients with acute ST elevation myocardial infarction (STEMI); group-3 comprised patients with Non-ST elevation myocardial infarction (Non-STEMI) and group-4 was the control group. All four groups were followed-up for 90 days for occurrence of cardiovascular events. Results: The CRP was elevated (>3 mg/L) among 27.6% patients in Group-1; 70.9% in group- 2; 77.9% in group-3 and 5.3% in the control group. Among cases with elevated CRP, 92.1% had a cardiac event compared to 34.3% among patients with CRP £3 mg/L (P < 0.0001). The mortality was significantly higher (P < 0.0001) in group-2 (8.9%) and group-3 (11.9%) as compared to group-1 (2.1%). There was no cardiac event or mortality in Group-4. Conclusions: Elevated CRP is a predictor of adverse outcome in patients with acute coronary syndromes and helps in identifying patients who may be at risk of cardiovascular complications.
  17 5,849 268
Transcatheter closure of patent ductus arteriosus using ADO device: Retrospective study of 149 patients
Sadiq M Al-Hamash, Hussein Abdul Wahab, Zayir H Khalid, Isam V Nasser
January-March 2012, 13(1):1-6
DOI:10.4103/1995-705X.96658  PMID:22754633
Background: Patent ductus arteriosus (PDA) is a common form of congenital heart disease and forms about 5-10% of congenital heart diseases. Surgical closure is safe and effective; however, certain patients may experience some morbidity. Recently, transcatheter closure of PDA using the Amplatzer duct occluder has been shown to be safe and efficacious. Objectives: To evaluate whether transcatheter closure with this device offers an alternative to surgical closure of PDA. Patients and Methods: Between July 2006 to July 2008, 149 patients (98 females and 51 males) with PDA underwent cardiac catheterization in an attempt to close their PDA by transcatheter approach using Amplatzer duct occluder device. Results: The patient's age ranged from 4 months to 45 years (median 5 years). Successful PDA closure was achieved in 136 patients (91.2%) with 100% complete closure rate within 24 hours after the procedure. Thirteen patients (8.7%) had unsuccessful attempts, 11 (7.3%) of them had failure of deployment of the device, while embolization of the device occurred in two of the patients (1.3%). Conclusions: Amplatzer duct occluder device is safe and effective for closure of different types and sizes of PDA with low rate of complication.
  14 10,142 349
Scorpion bite induced myocardial damage and pulmonary edema
Monika Maheshwari, CP Tanwar
January-March 2012, 13(1):16-18
DOI:10.4103/1995-705X.96663  PMID:22754636
A patient with electrocardiographic abnormalities after scorpion sting, simulating early myocardial infarction, is reported here. Pulmonary edema and congestive heart failure accompanied these electrocardiographic changes. The etiology of the cardiovascular manifestations in severe scorpion sting is related to the venom effects on the sympathetic nervous system and the adrenal secretion of catecholamines as well as to the toxic effects of the venom on the myocardium.
  9 4,516 173
The art of listening
Rachel Hajar
January-March 2012, 13(1):24-25
DOI:10.4103/1995-705X.96668  PMID:22754639
  4 3,886 116
Mitral-aortic intervalvular fibrosa aneurysm with rupture into left atrium: An uncommon cause of acute dyspnea
Nagaraja Moorthy, Sudeep Kumar, Satyendra Tewari, Aditya Kapoor, Nakul Sinha
January-March 2012, 13(1):13-15
DOI:10.4103/1995-705X.96662  PMID:22754635
Aneurysm of the mitral-aortic intervalvular fibrosa (MAIF) is an exceptionally rare but a potentially catastrophic complication, commonly following aortic valve endocarditis. We present a 24-year-old male presenting with acute onset dyspnea secondary to MAIF aneurysm rupturing into a left atrium causing large shunt which was diagnosed on echocardiography. The MAIF aneurysm in the absence of infective endocarditis rupturing into left atrium is extremely rare.
  2 5,026 139
Marfan's syndrome
Tanuj Bhatia, Aditya Kapoor, Sudeep Kumar
January-March 2012, 13(1):22-23
DOI:10.4103/1995-705X.96666  PMID:22754638
  1 3,666 161
Use of microvena snare catheter in non-ST elevation myocardial infarction due to saphenous vein graft occlusive thrombi
Mohammed Balghith
January-March 2012, 13(1):19-21
DOI:10.4103/1995-705X.96665  PMID:22754637
Percutaneous coronary intervention of grafts vessel is more challenging due to a higher incidence of periprocedural distal micro-emobilization and myocardial infarction. Percutaneous coronary intervention current guidelines advocate usage of distal embolic protection devices, especially in patients with a large thrombus burden, undergoing percutaneous intervention for vein graft disease. We present a 75-year-old man with acute coronary syndrome who had saphenous vein graft thrombus. This patient was treated successfully by manual aspiration of graft thrombus using a microvena catheter. There is yet no best available therapeutic options for patients undergoing percutaneous coronary intervention of saphenous vein graft lesions.
  - 3,360 72
Classics in cardiology: On cardiac murmurs* (Part 2)
Austin Flint
January-March 2012, 13(1):26-28
DOI:10.4103/1995-705X.96669  PMID:22754640
  - 2,869 128